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KMID : 0043320050280111213
Archives of Pharmacal Research
2005 Volume.28 No. 11 p.1213 ~ p.1218
Synthesis of New Triazolyl-N,N-Dialkyldithiocarbamates as Antifungal Agents
Ozkirimli Sumru

Apak T. Idil
Kiraz Muammer
Yegenoglu Yildiz
Abstract
N,N-Dialkylditihiocarbamate derivatives have been well known as broad-range fungicides. In this study, the triazole derivatives of ten new N,N-disubstituted dithiocarbamates (3a-j) were synthesized and their structures were identified by spectral and elemental analysis. Results of the antifungal activity studies showed that some of the compounds tested were active against M. canis, M. gypseum, and T rubrum at the concentration of 12.5 g/mL when c1otrimazol was used as a standard.
KEYWORD
Triazole derivatives, Dithiocarbamates, Antifungal agents
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